Most recently, Joshua brutally knocked out former UFC champion Francis Ngannou in the second round of their crossover bout in Saudi Arabia.
But on Saturday night, AJ will face his biggest test in recent years as he takes on Dubois, who goes into the fight on the back of an impressive win over Filip Hrgovic, which saw the 27-year-old become IBF heavyweight world champion.
DDD will put his strap on the line against Joshua, with the winner of the all-Brit clash likely to be in line to face the winner of Usyk's rematch with Tyson Fury.
When is Anthony Joshua vs Daniel Dubois?
Anthony Joshua vs Daniel Dubois will take place on Saturday, September 21.